Operating and Biocontainment Procedures of a Facility for Laboratory Mice with a Natural Microbiome: Immunophenotyping Procedure

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05:34 min

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December 13th, 2024

DOI :

10.3791/67100-v

December 13th, 2024

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¹BIH QUEST Center for Responsible Research, Berlin Institute of Health (BIH) at Charité - Universitätsmedizin Berlin, ²German Federal Institute for Risk Assessment (BfR), German Centre for the Protection of Laboratory Animals (Bf3R), ³Institute of Microbiology, Infectious Diseases and Immunology, Charité - Universitätsmedizin Berlin, corporate member of Freie Universität Berlin and Humboldt-Universität zu Berlin, ⁴Experimental and Clinical Research Center (ECRC) & Max-Delbrück-Centrum für Molekulare Medizin in der Helmholtz-Gemeinschaft (MDC), ⁵Department of Experimental Neurology, Charité - Universitätsmedizin Berlin, corporate member of Freie Universität Berlin and Humboldt-Universität zu Berlin, Klinik und Hochschulambulanz für Neurologie, ⁶Center for Stroke Research Berlin, Charité - Universitätsmedizin Berlin, corporate member of Freie Universität Berlin and Humboldt-Universität zu Berlin, ⁷Einstein Center for Neuroscience, ⁸German Center for Cardiovascular Research (DZHK), partner site Berlin, ⁹Department of Neuropathology, Charité - Universitätsmedizin Berlin, corporate member of Freie Universität Berlin and Humboldt-Universität zu Berlin, ¹⁰Cluster of Excellence, NeuroCure, ¹¹German Center for Neurodegenerative Diseases (DZNE) Berlin, ¹²Department of Hepatology and Gastroenterology, Charité - Universitätsmedizin Berlin, corporate member of Freie Universität Berlin and Humboldt-Universität zu Berlin, ¹³Institute of Animal Welfare, Animal Behavior and Laboratory Animal Science, Freie Universität Berlin, ¹⁴Forschungseinrichtungen für Experimentelle Medizin/FEM, Charité - Universitätsmedizin Berlin, corporate member of Freie Universität Berlin and Humboldt-Universität zu Berlin, ¹⁵Department of Pediatric Respiratory Medicine, Immunology and Critical Care Medicine, Charité - Universitätsmedizin Berlin, corporate member of Freie Universität Berlin and Humboldt-Universität zu Berlin, ¹⁶German Center for Lung Research (DZL), associated partner site, Berlin, ¹⁷Department of Infectious Diseases, Respiratory Medicine and Critical Care, Charité - Universitätsmedizin Berlin, corporate member of Freie Universität Berlin and Humboldt-Universität zu Berlin, ¹⁸Division of Toxicology, Institute of Clinical Pharmacology and Toxicology, Charité - Universitätsmedizin Berlin, corporate member of Freie Universität Berlin, Humboldt-Universität zu Berlin, and Berlin Institute of Health, ¹⁹Institute of Immunology, Charité-Universitätsmedizin Berlin, corporate member of Freie Universität Berlin and Humboldt-Universität zu Berlin, ²⁰German Cancer Research Center, ²¹German Cancer Consortium, partner site Berlin, ²²Department of Radiology (including Pediatric Radiology), Charité - Universitätsmedizin Berlin, corporate member of Freie Universität Berlin and Humboldt-Universität zu Berlin, ²³Department of Microbiome Research, University Hospital Erlangen, Friedrich-Alexander-Universität Erlangen-Nürnberg (FAU), ²⁴Department of Medicine II, Faculty of Medicine, Medical Center - University of Freiburg

Podsumowanie

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Laboratory Mice

Natural Microbiome

Immunophenotyping

Animal Husbandry

Biocontainment Procedures

Research Facility

Hygiene Standards

Immune Cell Populations

Preclinical Findings

Biomedical Research

Charit Universit tsmedizin Berlin

Rozdziały w tym wideo

0:00

Introduction

2:12

Sampling Blood from Wildling Mice Maintained with Natural Microbiomes

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