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Synthesis and Characterization of mRNA-Loaded Poly(Beta Aminoesters) Nanoparticles for Vaccination Purposes

4.3K Views

08:27 min

August 13th, 2021

DOI :

10.3791/62889-v

August 13th, 2021


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MRNA loaded Nanoparticles

Rozdziały w tym wideo

0:04

Introduction

1:00

Polyplexes Formation, Lyophilization, and Resuspension

2:44

In Vitro Characterization

4:34

In Vitro Functionality Tests: Capacity to Activate Model Immune Cells by Using Ovalbumin as Antigenic Model mRNA

6:24

Results: Nanoparticle Synthesis and Physicochemical Characterization, mRNA Encapsulation Efficiency, and In Vitro Results

7:45

Conclusion

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