Assay Development for High-Throughput Drug Screening Against Mycobacteria

1.4K Views

•

07:50 min

•

October 25th, 2024

DOI :

10.3791/66860-v

October 25th, 2024

•

Gabriel S. Oliveira¹^,², Clara M. Bento¹^,³^,⁴, António Pombinho¹^,³, Rita Reis¹^,³, Kevin Van Calster⁵^,⁶, Linda De Vooght⁵, André F. Maia¹^,³, Paul Cos⁵, Maria Salomé Gomes¹^,², Tânia Silva¹^,²

¹i3S – Instituto de Investigação e Inovação em Saúde da Universidade do Porto, ²ICBAS – Instituto de Ciências Biomédicas Abel Salazar, Universidade do Porto, ³IBMC - Instituto de Biologia Molecular e Celular, Universidade do Porto, ⁴Programa Doutoral em Biologia Molecular e Celular (MCBiology), Instituto de Ciências Biomédicas Abel Salazar da Universidade do Porto, ⁵Laboratory for Microbiology, Parasitology and Hygiene (LMPH), ⁶Department of Infectious Diseases in Humans, Immune Response, Sciensano

Summary

Explore More Videos

Assay Development

High throughput Drug Screening

Mycobacterium Abscessus

Antibiotic Resistance

I3S Technology

Double Reporter Strains

Drug Discovery Pipeline

Bacterial Targets

Compound Screening

Multi drug Regimen

Chapters in this video

0:00

Introduction

2:15

Antimicrobial Activity and Toxicity Assessment of Compounds Targeting Mycobacterium abscessus in Macrophage Infection Assays

Related Videos

10:05

High-throughput Detection Method for Influenza Virus

26.1K Views

09:28

Quantitative High-throughput Single-cell Cytotoxicity Assay For T Cells

14.9K Views

12:02

Assays for the Identification of Novel Antivirals against Bluetongue Virus

13.9K Views

15:28

A Microscopic Phenotypic Assay for the Quantification of Intracellular Mycobacteria Adapted for High-throughput/High-content Screening

7.7K Views

11:34

High-throughput Screening for Broad-spectrum Chemical Inhibitors of RNA Viruses

13.7K Views

05:46

Rapid Screening of HIV Reverse Transcriptase and Integrase Inhibitors

17.7K Views

10:00

High-throughput Quantitative Real-time RT-PCR Assay for Determining Expression Profiles of Types I and III Interferon Subtypes

13.3K Views

15:29

Microscopy-based Assays for High-throughput Screening of Host Factors Involved in Brucella Infection of Hela Cells

8.2K Views

08:43

A Fluorescence-based Lymphocyte Assay Suitable for High-throughput Screening of Small Molecules

10.3K Views

10:29

A High-throughput Compatible Assay to Evaluate Drug Efficacy against Macrophage Passaged Mycobacterium tuberculosis

7.7K Views