JoVE Journal
Neuroscience
You have full access to this content through
Nanyang Technological UniversityEstablishment of an Electrophysiological Platform for Modeling ALS with Regionally-Specific Human Pluripotent Stem Cell-Derived Astrocytes and Neurons
2.2K Views
•
11:52 min
•
August 26th, 2021
DOI :
August 26th, 2021
•Explore More Videos
Chapters in this video
0:04
Introduction
0:48
Maintaining Non-Confluent Human Induced Pluripotent Stem Cells
2:58
Diffrentiation of NPC into Motor Neuron
3:46
Co-Culturing Motor Neurons and Astrocytes in Multi-Electrode Array Plates
7:42
Multi-Electrode Array Recording
8:16
Pharmacological Assays on Multi-Electrode Array
9:01
Results: Human Pluripotent Stem Cell-Derived Motor Neurons and Astrocytes
11:09
Conclusion
Related Videos
Rapid Neuronal Differentiation of Induced Pluripotent Stem Cells for Measuring Network Activity on Micro-electrode Arrays
26.9K Views
Synaptic Microcircuit Modeling with 3D Cocultures of Astrocytes and Neurons from Human Pluripotent Stem Cells
12.2K Views
Conversion of Human Induced Pluripotent Stem Cells (iPSCs) into Functional Spinal and Cranial Motor Neurons Using PiggyBac Vectors
11.3K Views
Generation of Human Neurons and Oligodendrocytes from Pluripotent Stem Cells for Modeling Neuron-Oligodendrocyte Interactions
4.7K Views
In vitro Modeling for Neurological Diseases using Direct Conversion from Fibroblasts to Neuronal Progenitor Cells and Differentiation into Astrocytes
4.9K Views
Real-Time Fluorescent Measurement of Synaptic Functions in Models of Amyotrophic Lateral Sclerosis
2.6K Views
Primary Cultures of Rat Astrocytes and Microglia and Their Use in the Study of Amyotrophic Lateral Sclerosis
3.3K Views
A Multi-Electrode Array Platform for Modeling Epilepsy Using Human Pluripotent Stem Cell-Derived Brain Assembloids
1.2K Views
Automated Production of Human Induced Pluripotent Stem Cell-Derived Cortical and Dopaminergic Neurons with Integrated Live-Cell Monitoring
7.2K Views
Differentiation of Spinal Cord Neural Progenitor Cells into Motor Neurons
74 Views
ISSN 1940-087X
Copyright © 2025 MyJoVE Corporation. All rights reserved
We use cookies to enhance your experience on our website.
By continuing to use our website or clicking “Continue”, you are agreeing to accept our cookies.