A Small Animal Model of Ex Vivo Normothermic Liver Perfusion

13.3K Views

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08:32 min

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June 27th, 2018

DOI :

10.3791/57541-v

June 27th, 2018

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Eliza W. Beal¹^,², Curtis Dumond¹, Jung-Lye Kim¹^,², Clifford Akateh¹^,², Emre Eren¹, Katelyn Maynard¹, Chandan K. Sen³, Jay L. Zweier⁴, Kenneth Washburn², Bryan A. Whitson¹^,³, Sylvester M. Black¹^,²

¹Collaboration for Organ Perfusion, Protection, Engineering and Regeneration (COPPER) Lab, Division of Transplant, Department of Surgery, Comprehensive Transplant Center, Ohio State University Wexner Medical Center, ²Department of Surgery, Division of Transplant, Ohio State University Wexner Medical Center, ³Department of Surgery, Division of CardioThoracic Surgery, Ohio State University Wexner Medical Center, ⁴Department of Medicine, Ohio State University Wexner Medical Center

Summary

Chapters in this video

0:04

Title

0:36

Preparation of the Portal Vein Cuff and Bile Duct Cannula

1:20

Liver Procurement Procedure

5:24

Ex Vivo Normothermic Liver Perfusion

6:58

Results: Analysis of Tissue Damage in Base Perfusate-only and Base Perfusate and Plus PEG-CAT Groups

7:56

Conclusion

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