Three-dimensional Tissue Engineered Aligned Astrocyte Networks to Recapitulate Developmental Mechanisms and Facilitate Nervous System Regeneration
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08:52 min
•
January 10th, 2018
DOI :
January 10th, 2018
•Kritika S. Katiyar*1,2,3, Carla C. Winter*1,2,4, Wisberty J. Gordián-Vélez1,2,4, John C. O'Donnell1,2, Yeri J. Song1,5, Nicole S. Hernandez1,5, Laura A. Struzyna1,2,4, D. Kacy Cullen1,2,5
1Center for Brain Injury & Repair, Department of Neurosurgery, Perelman School of Medicine, University of Pennsylvania, 2Center for Neurotrauma, Neurodegeneration & Restoration, Michael J. Crescenz Veterans Affairs Medical Center, 3School of Biomedical Engineering, Drexel University, 4Department of Bioengineering, School of Engineering and Applied Sciences, University of Pennsylvania, 5Neuroscience Graduate Group, Perelman School of Medicine, University of Pennsylvania
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Chapters in this video
0:05
Title
1:03
Agarose Hydrogel Micro-Column Fabrication
3:51
ECM Core Fabrication
5:26
Seeding Micro-columns with Astrocytes
6:32
Results: Formation of Astrocyte Bundles within Hydrogel Micro-columns over Time
7:54
Conclusion
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