Induction of an Isoelectric Brain State to Investigate the Impact of Endogenous Synaptic Activity on Neuronal Excitability In Vivo

8.0K Views

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10:19 min

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March 31st, 2016

DOI :

10.3791/53576-v

March 31st, 2016

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Tristan Altwegg-Boussac¹^,²^,³^,⁴, Séverine Mahon¹^,²^,³^,⁴, Mario Chavez¹^,²^,³^,⁴, Stéphane Charpier¹^,²^,³^,⁴, Adrien E. Schramm¹^,²^,³^,⁴

¹Inserm U1127, ²CNRS UMR 7225, ³UPMC Univ Paris 06, UMR S 1127, Sorbonne Universités, ⁴Institut du Cerveau et de la Moelle épinière (ICM)

Summary

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Keywords Isoelectric Brain State

Neuronal Excitability

Physiological Monitoring

Stereotaxic Frame

Chapters in this video

0:05

Title

0:47

Surgical Preparation

5:21

Intracellular Recordings

6:54

Induce the Isoelectric State

8:27

Results: Consequences of Synaptic Activity Suppression on the Membrane Potential Dynamics and on Cortical Neurons Excitability

9:44

Conclusion

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