JoVE Journal

Neuroscience

This content is Open Access.

Ultrasound-Guided Microinjection into the Mouse Forebrain In Utero at E9.5

Transcript

In utero survival surgery in mice permits the molecular manipulation of gene expression during development. Here we describe the use of high-frequency ultrasound imaging to guide the injection of retroviral vectors into the mouse brain at embryonic day (E) 9.5.

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