Микрожидком система с поверхности паттернирования для исследования кавитационного пузырька (ы) -клетка взаимодействия и результирующая биоэффектов на уровне одной клетки

A microfluidic chip was fabricated to produce pairs of gold dots for tandem bubble generation and fibronectin-coated islands for single-cell patterning nearby. The resultant flow field was characterized by particle image velocimetry and was employed to study various bioeffects, including cell membrane poration, membrane deformation, and intracellular calcium response.