Um sistema microfluídico com padrões de superfície para investigar bolha de cavitação (s) Interação -cell e os Efeitos Biológicos resultante no nível de célula única

A microfluidic chip was fabricated to produce pairs of gold dots for tandem bubble generation and fibronectin-coated islands for single-cell patterning nearby. The resultant flow field was characterized by particle image velocimetry and was employed to study various bioeffects, including cell membrane poration, membrane deformation, and intracellular calcium response.