Hi-C: A Method to Study the Three-dimensional Architecture of Genomes.

Please note that all translations are automatically generated. Click here for the English version.

408.5K Views

•

22:27 min

•

May 6th, 2010

DOI :

10.3791/1869-v

May 6th, 2010

•

Nynke L. van Berkum*¹, Erez Lieberman-Aiden*²^,³^,⁴^,⁵, Louise Williams*², Maxim Imakaev⁶, Andreas Gnirke², Leonid A. Mirny³^,⁶, Job Dekker¹, Eric S. Lander²^,⁷^,⁸

¹Program in Gene Function and Expression, Department of Biochemistry and Molecular Pharmacology, University of Massachusetts Medical School, ²Broad Institute of Harvard and Massachusetts Institute of Technology, ³Division of Health Sciences and Technology, Massachusetts Institute of Technology, ⁴Program for Evolutionary Dynamics, Department of Organismic and Evolutionary Biology, Department of Mathematics, Harvard University , ⁵Department of Applied Mathematics, Harvard University , ⁶Department of Physics, Massachusetts Institute of Technology, ⁷Department of Systems Biology, Harvard Medical School, ⁸Department of Biology, Massachusetts Institute of Technology

Podsumowanie

Przeglądaj więcej filmów

Hi C

Three dimensional Architecture Of Genomes

Chromosomal Interactions

Chromosome Conformation Capture 3C

Genome wide Studies

Hi C Method

DNA protein Cross links

Biotinylated Residue

Ligation Products

Rozdziały w tym wideo

0:00

Title

2:07

Crosslinking, Digestion, Marking of DNA Ends, and Blunt-End Ligation

9:46

Shearing and Size Selection

1:03

Introduction

16:38

Representative Hi-C Results

12:03

Biotin Pull-Down and Paired End Sequencing

21:32

Conclusion

Powiązane Filmy

12:30

Badania wizualne Wrażliwość na prędkość i kierunek ruchu w Jaszczurki

11.4K Views

26:43

Computer-Generated Animal Model Stimuli

10.9K Views

07:29

A high-throughput method to globally study the organelle morphology in S. cerevisiae

10.3K Views

11:49

Using High Resolution Computed Tomography to Visualize the Three Dimensional Structure and Function of Plant Vasculature

21.0K Views

07:34

Slide Preparation Method to Preserve Three-dimensional Chromatin Architecture of Testicular Germ Cells

7.3K Views

09:47

FRET Imaging in Three-dimensional Hydrogels

13.0K Views

12:38

Three-dimensional Reconstruction of the Vascular Architecture of the Passive CLARITY-cleared Mouse Ovary

8.6K Views

08:17

A Proximal Culture Method to Study Paracrine Signaling Between Cells

9.4K Views

08:52

Adipo-Clear: A Tissue Clearing Method for Three-Dimensional Imaging of Adipose Tissue

26.9K Views

11:15

Quadruple-Checkerboard: A Modification of the Three-Dimensional Checkerboard for Studying Drug Combinations

4.4K Views