Desarrollo de un modelo de colitis impulsado por el antígeno para el Estudio de la presentación de antígenos por células presentadoras de antígenos a las células T

In this antigen-driven colitis model, OT-II CD4⁺ T cells expressing a red fluorescent protein were adoptively transferred into RAG^-/- mice that express a green fluorescent protein in mononuclear phagocytes (MPs). The hosts were challenged with Escherichia coli (E.coli) expressing the ovalbumin protein (OVA) fused to a cyan fluorescent protein (CFP).