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Bioengineering

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Nanyang Technological University

Artificial Lung Device Priming for In Situ Fiber Bundle Surface Grafting

320 Views

•

08:53 min

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March 28th, 2025

DOI :

10.3791/67271-v

March 28th, 2025

•

Romario Pusey*¹, Sarah Majin¹, Amir Mokhammad¹, Betelihem Fre¹, Kebisha Basukala¹, Chika G. Okwuogori¹, Keith Cook*²^,³, Rei Ukita⁴, William Grogan⁵, David Skoog*², Kagya Amoako*¹

¹Department of Chemistry and Chemical & Biomedical Engineering, University of New Haven, ²Advanced Respiratory Technologies, LLC, ³Department of Biomedical Engineering, Carnegie Mellon University, ⁴Department of Cardiac Surgery, Vanderbilt University Medical Center, ⁵Auburn University

Summary

This study investigated the antifouling activity of artificial lung hollow fibers coated by priming the lung device. While this surface modification of fibers approach is practical, the effectiveness of the coating process depends on the graft coverage across fiber mat layers within the bundle.

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artificial lung

gas exchange fiber bundle

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Chapters in this video

0:00

Introduction

1:31

Coating the Artificial Lung Circuit Using a Two-Step Zwitterionic DOPA-SBMA Grafting Approach

3:58

Evaluation of Protein Fouling on Coated Lung Circuit Materials

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