JoVE Journal

Chemistry

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A Microfluidic Approach for the Study of Ice and Clathrate Hydrate Crystallization

The present protocol describes the crystallization of microscopic ice crystals and clathrate hydrates in microfluidic devices, enabling liquid exchange around the formed crystals. This provides unparalleled possibilities to examine the crystallization process and binding mechanisms of the inhibitors.

Chapters in this video

0:04

Introduction

0:37

Microfluidic Device Fabrication

2:45

Setting up the Microfluidic Device and Formation of Single Crystals in the Microfluidic Channels

4:23

Solution Exchange Around Single Crystals

4:47

Experiments with Clathrate Hydrates

5:59

Results: Crystallization of Microscopic Ice Crystals and Clathrate Hydrates in Microfluidic Devices

7:10

Conclusion

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