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A Human Blood-Brain Interface Model to Study Barrier Crossings by Pathogens or Medicines and Their Interactions with the Brain

8.6K Views

07:52 min

April 9th, 2019

DOI :

10.3791/59220-v

April 9th, 2019


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Human Blood Brain Interface

Chapters in this video

0:04

Title

0:36

Human Cerebral Microvascular Endothelial Cell (hCMEC)/D3 Insert Coating and Blood Brain Barrier (BBB) Preparation

2:48

BBB-Minibrain Endothelial Permeability Validation

3:38

BBB Crossing and Multiplication of Yellow Fever Viruses in the Minibrain and Biomolecule BBB Crossing and Brain Cell Targeting

5:22

Results: Representative BBB-Minibrain Testing of Neuroinvasive Variants and Biomolecule Properties

7:19

Conclusion

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