An HS-MRM Assay for the Quantification of Host-cell Proteins in Protein Biopharmaceuticals by Liquid Chromatography Ion Mobility QTOF Mass Spectrometry
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11:09 min
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April 17th, 2018
DOI :
April 17th, 2018
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Chapters in this video
0:04
Title
0:44
Setup of the LC/HDMSE (High Definition MSE) Data Acquisition Method
3:59
Setup of the Tof-MRM Method for Collision Energy Optimization and the Final HS-MRM Acquisition Method for Peptide Quantification
7:42
Creation of a Processing Method for the Analysis of the HS-MRM Dataset
9:57
Results: An HS-MRM Assay for Quantification of Host-cell Protein Peptides in a Monoclonal Antibody Digest
10:29
Conclusion
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