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Nanyang Technological University

Continuous Manual Exchange Transfusion for Patients with Sickle Cell Disease: An Efficient Method to Avoid Iron Overload

19.2K Views

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05:23 min

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March 14th, 2017

DOI :

10.3791/55172-v

March 14th, 2017

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Bérengère Koehl¹, Florence Missud¹, Laurent Holvoet¹, Ghislaine Ithier¹, Oliver Sakalian-Black², Zinedine Haouari¹, Emmanuelle Lesprit³, André Baruchel⁴, Malika Benkerrou¹

¹Reference Centre of Sickle Cell Disease, Hematology Unit, Robert Debré Hospital, AP-HP, ²School of Pharmacy, Université Paris Descartes, ³Etablissement Français du Sang, Robert Debré Hospital, AP-HP, ⁴Hematology Unit,, Robert Debré Hospital, AP-HP, Univsité Paris Diderot

Summary

We have outlined a method of continuous manual exchange transfusion for the treatment of sickle cell disease in patients. This safe protocol was designed to effectively limit iron overload in patients in need of chronic transfusions and can be used extensively without any special equipment.

Explore More Videos

Sickle Cell Disease

Continuous Manual Exchange Transfusion

Packed Red Blood Cells

Hemodynamic Parameters

Chapters in this video

0:05

Title

0:54

Patient and Blood Product Preparation

2:20

Optional Initial Isovolemic Phlebotomy

3:25

Isovolemic Exchange Transfusion and Final Laboratory Test

4:13

Results: Representative Iron Overloads during Manual Exchange Transfusion or Erythrapheresis Programs

4:54

Conclusion

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