Mimicking the Function of Signaling Proteins: Toward Artificial Signal Transduction Therapy

0:45

Synthesis and Operating Principles of the 'Chemical Transducer'

1:51

Setting Up the Plate Reader for Kinetic Measurement

3:26

Measuring GST Activity in the Presence of the 'Chemical Transducer' and PDGF

4:59

Evaluating GST Activation/Inhibition Cycles Mediated by the 'Chemical Transducer'

6:37

Evaluating the Real-time Effect of PDGF Addition

7:42

Measuring JS-K Prodrug Activation by GST in the Presence of the 'Chemical Transducer' and PDGF

10:16

Results: 'Chemical Transducer' Induces Artificial Communication Between PDFG and GST

11:53

Conclusion