Generation of Organ-conditioned Media and Applications for Studying Organ-specific Influences on Breast Cancer Metastatic Behavior

8.4K Views

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09:44 min

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June 13th, 2016

DOI :

10.3791/54037-v

June 13th, 2016

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Matthew M. Piaseczny*¹^,², Graciella M. Pio*¹^,², Jenny E. Chu¹^,², Ying Xia¹, Kim Nguyen¹^,³, David Goodale¹, Alison Allan¹^,²^,⁴^,⁵

¹London Regional Cancer Program, London Health Sciences Centre, ²Department of Anatomy & Cell Biology, Schulich School of Medicine & Dentistry, Western University, ³Department of Biochemistry, Schulich School of Medicine & Dentistry, Western University, ⁴Department of Oncology, Schulich School of Medicine & Dentistry, Western University, ⁵Lawson Health Research Institute

Summary

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Keywords Organ conditioned Media

Organ specific Factors

Breast Cancer Metastasis

Chapters in this video

0:05

Title

0:47

Lymph Node (LN), Lung, Leg Bones, and Brain Isolation

3:29

Lung- or Brain-conditioned Medium Generation

4:53

Bone Marrow- or LN-conditioned Medium Generation

6:58

Results: Representative Organ-specific Influences on Breast Cancer Metastatic Behavior

8:35

Conclusion

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