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In Situ Detection of Autoreactive CD4 T Cells in Brain and Heart Using Major Histocompatibility Complex Class II Dextramers

11.6K Views

13:10 min

August 1st, 2014

DOI :

10.3791/51679-v

August 1st, 2014


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MHC Class II Dextramers

Chapters in this video

0:05

Title

1:49

In Situ Staining of Cerebral Sections with MHC Class II (IAs)/PLP 139-151 Dextramers

6:28

Analysis of Dextramer+ (dext+) CD4+ T Cells by Laser Scanning Confocal Microscopy (LSCM)

10:50

Results: In Situ Detection of Antigen-specific Autoreactive CD4 T Cells by Direct Staining with MHC Class II Dextramers

12:29

Conclusion

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