Integração de Wet and Processes bancada secos Otimiza alvejado Seqüenciamento Next-geração de baixa qualidade e biópsias de tumores de baixa quantidade

An integrated system for targeted next-generation sequencing of oncology specimens is described. This cross-platform system is optimized for low-quality and low-quantity tumor biopsies, accommodates low DNA inputs, includes well-characterized multi-variant controls, and features a novel variant caller that is informed by quantitative pre-analytical quality control measures.