Induction of Nephrotic Syndrome in Mice by Retrobulbar Injection of Doxorubicin and Prevention of Volume Retention by Sustained Release Aprotinin

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8.3K Views

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07:38 min

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May 6th, 2018

DOI :

10.3791/57642-v

May 6th, 2018

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Bernhard N. Bohnert¹^,²^,³, Ferruh Artunc¹^,²^,³

¹Department of Internal Medicine, Division of Endocrinology, Diabetology, Vascular Disease, Nephrology and Clinical Chemistry, University Hospital Tübingen, ²Institute of Diabetes Research and Metabolic Diseases (IDM) of the Helmholtz Center Munich, University Tübingen, ³German Center for Diabetes Research (DZD), University Tübingen

Podsumowanie

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Keywords Nephrotic Syndrome

Doxorubicin

Retrobulbar Injection

Chronic Kidney Disease

Mouse Model

Experimental Protocol

Surgical Procedure

Rozdziały w tym wideo

0:04

Title

0:54

Inducing Experimental Nephrotic Syndrome with Doxorubicin

2:24

Implantation of Sustained-Release Pellets Containing Aprotinin

4:01

Assessing Urine Serine Protease Activity

5:32

Results: Analysis of Doxorubicin-induced Nephrotic Syndrome

6:48

Conclusion

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