A Chronic Autoimmune Dry Eye Rat Model with Increase in Effector Memory T Cells in Eyeball Tissue

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11.4K Views

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09:42 min

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June 7th, 2017

DOI :

10.3791/55592-v

June 7th, 2017

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Aihua Hou¹^,², Tanima Bose³, K. George Chandy³, Louis Tong¹^,²^,⁴^,⁵

¹Singapore Eye Research Insitute, A Member of SingHealth, ²DUKE-National University of Singapore Medical School, ³Lee Kong Chian School of Medicine, Nanyang Technological University, ⁴Singapore National Eye Center, ⁵Yong Loo Lin School of Medicine, National University of Singapore

Podsumowanie

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Keywords Autoimmune Dry Eye

Rat Model

Lacrimal Gland

Effector Memory T Cells

Ocular Disease

Lymphocyte Trafficking

Sprague Dawley Rat

Lacrimal Gland Extract

Freund s Adjuvant

Ovalbumin

Rozdziały w tym wideo

0:05

Title

8:57

Conclusion

7:19

Results

1:18

Preparation of Lacrimal Gland Extract

2:32

Preparation of Emulsion

3:30

Immunization of Lewis Rats and Injection of Antigen Mixture into the Forniceal Subconjunctiva and Lacrimal Gland

4:53

Assessment of Dry Eye Features

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