Polyelectrolyte Complex for Heparin Binding Domain Osteogenic Growth Factor Delivery

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7.5K Views

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12:27 min

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August 22nd, 2016

DOI :

10.3791/54202-v

August 22nd, 2016

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Raymond Wing Moon Lam¹, Sunny Akogwu Abbah², Wang Ming¹, Mathanapriya Naidu¹, Felly Ng¹, Hu Tao¹, James Goh Cho Hong³^,⁴, Kang Ting⁵, Wong Hee Kit¹^,⁴

¹Department of Orthopaedic Surgery, Yong Loo Lin School of Medicine, National University of Singapore, ²Centre for Research in Medical Devices (CÚRAM), National University of Ireland Galway, ³Department of Bioengineering, Faculty of Engineering, National University of Singapore, ⁴Tissue Engineering Program, National University of Singapore, ⁵Department of Orthopaedic Surgery and the Orthopaedic Hospital Research Center, University of California, Los Angeles

Podsumowanie

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Keywords Polyelectrolyte Complex

Heparin Binding Domain

Osteogenic Growth Factor

Growth Factor Entrapment

Growth Factor Release

Rozdziały w tym wideo

0:05

Title

0:49

Alginate Microbead Fabrication

3:31

Size Measurement and Sterilization of Alginate Microbeads

5:29

Protamine and Heparin Coating

6:38

BMP-2 and NELL-1 Uptake and Release

7:43

In Vitro Bioactivity of NELL-1 and BMP-2 & NELL-1 Loading into PEC Scaffold

9:57

Results: Analysis of the Polyelectrolyte Complex for Growth Factor Uptake Fabrication Process

11:28

Conclusion

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