Morris Water Maze Test: Optimization for Mouse Strain and Testing Environment

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21.4K Views

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10:24 min

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June 22nd, 2015

DOI :

10.3791/52706-v

June 22nd, 2015

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Daniel S. Weitzner¹, Elizabeth B. Engler-Chiurazzi², Linda A. Kotilinek³, Karen Hsiao Ashe³^,⁴^,⁵, Miranda Nicole Reed¹^,⁶

¹Department of Psychology, Behavioral Neuroscience, West Virginia University, ²Department of Physiology and Pharmacology, West Virginia University, ³Department of Neurology, N. Bud Grossman Center for Memory Research and Care, University of Minnesota, ⁴Department of Neuroscience, N. Bud Grossman Center for Memory Research and Care, University of Minnesota, ⁵GRECC, VA Medical Center, ⁶Center for Neuroscience, Center for Basic and Translational Stroke Research, West Virginia University

Podsumowanie

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Keywords Morris Water Maze

Transgenic Mouse Models

Alzheimer s Disease

P301L Tau

RTg TauP301L 4510 Mice

FVB N

129S6 Background

Rozdziały w tym wideo

0:05

Title

1:26

Acclimation Protocol

2:56

Visible Platform Training

5:10

Morris Water Maze Hidden Platform Training

7:25

Probe Trials

8:34

Results: TauP301L Expression Affects Performance in the Morris Water Maze

9:59

Conclusion

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