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Chapter 9

Translation: RNA to Protein

Tłumaczenie
Tłumaczenie
Lesson: Translation Translation is the process of synthesizing proteins from the genetic information carried by messenger RNA (mRNA). Following ...
Aktywacja tRNA
Aktywacja tRNA
Aminoacyl-tRNA synthetases are present in both eukaryotes and bacteria. Though eukaryotes have 20 different aminoacyl-tRNA synthetases to couple to 20 ...
Rybosomów
Rybosomów
Ribosomes translate genetic information encoded by messenger RNA (mRNA) into proteins. Both prokaryotic and eukaryotic cells have ribosomes. Cells that ...
Poprawa dokładności translacji
Poprawa dokładności translacji
Base complementarity between the three base pairs of mRNA codon and the tRNA anticodon is not a failsafe mechanism. Inaccuracies can range from a single ...
Rozpoczęcie tłumaczenia
Rozpoczęcie tłumaczenia
Initiating translation is complex because it involves multiple molecules. Initiator tRNA, ribosomal subunits, and eukaryotic initiation factors (eIFs) are ...
Zakończenie tłumaczenia
Zakończenie tłumaczenia
The large ribosomal subunit has several important structures essential to translation. These include the peptidyl transferase center (PTC) - which is the ...
Rozpad mRNA za pośrednictwem nonsensu
Rozpad mRNA za pośrednictwem nonsensu
The Upf proteins that carry out nonsense-mediated decay (NMD) are found in all eukaryotic organisms, including humans. Each protein has an individual ...
Molekularne białka opiekuńcze i fałdowanie białek
Molekularne białka opiekuńcze i fałdowanie białek
The native conformation of a protein is formed by interactions between the side chains of its constituent amino acids. When the amino acids cannot form ...
Proteasom
Proteasom
Eukaryotic cells can degrade proteins through several pathways. One of the most important amongst these is the ubiquitin-proteasome pathway. It helps the ...
Regulowana degradacja białek
Regulowana degradacja białek
It is vital to regulate the activity of enzymatic as well as non-enzymatic proteins inside the cell. This can be achieved either through creating a ...
Białka: od genów do degradacji
Białka: od genów do degradacji
Within a biological system, the DNA encodes the RNA, and the nucleotide sequence in the RNA further defines the amino acid sequence in the protein. This ...
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