Procoagulant Platelet Characterization by Measuring Phosphatidylserine Exposure and Microvesicle Release from Human Purified PlateletsMathieu Fiore 1,2,3, Alexandre Guy 2,3, Chloé James 2,3
1French Reference Centre for Inherited Platelet Disorders, University Hospital of Bordeaux, 2Department of Haematology, University Hospital of Bordeaux, 3Inserm U1034, Biology of Cardiovascular Disease
Procoagulant platelet formation has been correlated with an increased risk of thrombosis. Presented here is a precise protocol for isolating washed platelets from human blood, intended to quantify the exposure of phosphatidylserine and microvesicle release, which are distinctive features of procoagulant platelets.
