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Johan Gobom

Inst. of Neuroscience and Physiology,
Dept. of Psychiatry and Neurochemistry,
Inst. of Neuroscience and Physiology, Dept. of Psychiatry and Neurochemistry

Sahlgrenska Academy at University of Gothenburg

BIOGRAPHY

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PUBLICATIONS

Neurogranin in cerebrospinal fluid as a marker of synaptic degeneration in Alzheimer's disease.

Brain research Nov, 2010 | Pubmed ID: 20875798

An online nano-LC-ESI-FTICR-MS method for comprehensive characterization of endogenous fragments from amyloid β and amyloid precursor protein in human and cat cerebrospinal fluid.

Journal of mass spectrometry : JMS May, 2012 | Pubmed ID: 22576872

Peptidome analysis of cerebrospinal fluid by LC-MALDI MS.

PloS one , 2012 | Pubmed ID: 22880031

Reference measurement procedures for Alzheimer's disease cerebrospinal fluid biomarkers: definitions and approaches with focus on amyloid β42.

Biomarkers in medicine Aug, 2012 | Pubmed ID: 22917143

A single dose of the γ-secretase inhibitor semagacestat alters the cerebrospinal fluid peptidome in humans.

Alzheimer's research & therapy , 2016 | Pubmed ID: 26948580

Reference measurement procedure for CSF amyloid beta (Aβ)1-42 and the CSF Aβ1-42 /Aβ1-40 ratio - a cross-validation study against amyloid PET.

Journal of neurochemistry Aug, 2016 | Pubmed ID: 27579672

Expanding the cerebrospinal fluid endopeptidome.

Proteomics Mar, 2017 | Pubmed ID: 28044435

Ex vivo (18)O-labeling mass spectrometry identifies a peripheral amyloid β clearance pathway.

Molecular neurodegeneration Feb, 2017 | Pubmed ID: 28219449

A novel quantification-driven proteomic strategy identifies an endogenous peptide of pleiotrophin as a new biomarker of Alzheimer's disease.

Scientific reports Oct, 2017 | Pubmed ID: 29042634

INSTITUTIONS

Sahlgrenska Academy at University of Gothenburg

Sahlgrenska University Hospital

Sahlgrenska Academy at University of Gothenburg

JOVE ARTICLES

Sample Preparation for Endopeptidomic Analysis in Human Cerebrospinal Fluid

Karl T. Hansson¹,

Tobias Skillbäck^1,2,

Elin Pernevik¹,

Jessica Holmén-Larsson¹,

Gunnar Brinkmalm¹,

Kaj Blennow^1,2,

Henrik Zetterberg^1,2,3,

Johan Gobom^1,2

¹Inst. of Neuroscience and Physiology, Dept. of Psychiatry and Neurochemistry, Sahlgrenska Academy at University of Gothenburg,

²Clinical Neurochemistry Laboratory, Sahlgrenska University Hospital,

³Department of Molecular Neuroscience, UCL Institute of Neurology

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Johan Gobom

.css-o250i3{font-size:18px;font-family:Open Sans,sans-serif;line-height:21.6px;}Inst. of Neuroscience and Physiology,Dept. of Psychiatry and Neurochemistry,Inst. of Neuroscience and Physiology, Dept. of Psychiatry and Neurochemistry

Sahlgrenska Academy at University of Gothenburg

Sample Preparation for Endopeptidomic Analysis in Human Cerebrospinal Fluid

Inst. of Neuroscience and Physiology,
Dept. of Psychiatry and Neurochemistry,
Inst. of Neuroscience and Physiology, Dept. of Psychiatry and Neurochemistry