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Drug Discovery and Development
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Synthesis and structure-activity relationship (SAR) of 2-methyl-4-oxo-3-oxetanylcarbamic acid esters, a class of potent N-acylethanolamine acid amidase (NAAA) inhibitors.
Journal of medicinal chemistry Sep, 2013 | Pubmed ID: 23991897
Synthesis, structure-activity, and structure-stability relationships of 2-substituted-N-(4-oxo-3-oxetanyl) N-acylethanolamine acid amidase (NAAA) inhibitors.
ChemMedChem Feb, 2014 | Pubmed ID: 24403170
Advances in the discovery of N-acylethanolamine acid amidase inhibitors.
Pharmacological research Aug, 2014 | Pubmed ID: 24798679
β-Lactones Inhibit N-acylethanolamine Acid Amidase by S-Acylation of the Catalytic N-Terminal Cysteine.
ACS medicinal chemistry letters May, 2012 | Pubmed ID: 24900487
Synthesis, biological evaluation, and 3D QSAR study of 2-methyl-4-oxo-3-oxetanylcarbamic acid esters as N-acylethanolamine acid amidase (NAAA) inhibitors.
Journal of medicinal chemistry Dec, 2014 | Pubmed ID: 25380517
Activity-Based Probe for N-Acylethanolamine Acid Amidase.
ACS chemical biology Sep, 2015 | Pubmed ID: 26102511
Potent α-amino-β-lactam carbamic acid ester as NAAA inhibitors. Synthesis and structure-activity relationship (SAR) studies.
European journal of medicinal chemistry Mar, 2016 | Pubmed ID: 26866968
Istituto Italiano di Tecnologia
Elisa Romeo1,
Silvia Pontis1,
Stefano Ponzano1,
Fabiola Bonezzi1,
Marco Migliore1,
Simona Di Martino1,
Maria Summa1,
Daniele Piomelli1,2
1Drug Discovery and Development, Istituto Italiano di Tecnologia,
2Departments of Anatomy and Neurobiology, Pharmacology, and Biological Chemistry, University of California, Irvine School of Medicine
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