Jonathan V. Sweedler

Two toxins from Conus striatus that individually induce tetanic paralysis.

Targeted single-cell microchemical analysis: MS-based peptidomics of individual paraformaldehyde-fixed and immunolabeled neurons.

Evaluation of database search programs for accurate detection of neuropeptides in tandem mass spectrometry experiments.

Multifactorial Understanding of Ion Abundance in Tandem Mass Spectrometry Experiments.

The ctenophore genome and the evolutionary origins of neural systems.

Analysis of endogenous nucleotides by single cell capillary electrophoresis-mass spectrometry.

Identification of best indicators of peptide-spectrum match using a permutation resampling approach.

Mass spectrometry-based characterization of endogenous peptides and metabolites in small volume samples.

Peptidomics for the discovery and characterization of neuropeptides and hormones.

Peptidomics and Secretomics of the Mammalian Peripheral Sensory-Motor System.

Mass Spectrometry Imaging and Identification of Peptides Associated with Cephalic Ganglia Regeneration in Schmidtea mediterranea.

A one-step matrix application method for MALDI mass spectrometry imaging of bacterial colony biofilms.

Dopamine-modified TiO monolith-assisted LDI MS imaging for simultaneous localization of small metabolites and lipids in mouse brain tissue with enhanced detection selectivity and sensitivity.

microMS: A Python Platform for Image-Guided Mass Spectrometry Profiling.

3D-Printed pHEMA Materials for Topographical and Biochemical Modulation of Dorsal Root Ganglion Cell Response.

Improved identification and quantitation of mature endogenous peptides in the rodent hypothalamus using a rapid conductive sample heating system.

Bioinformatics for Prohormone and Neuropeptide Discovery.

Non-targeted Identification of D-Amino Acid-Containing Peptides Through Enzymatic Screening, Chiral Amino Acid Analysis, and LC-MS.

Peptide identifications and false discovery rates using different mass spectrometry platforms.

Exploring the Sea Urchin Neuropeptide Landscape by Mass Spectrometry.

Conformational investigation of the structure-activity relationship of GdFFD and its analogues on an achatin-like neuropeptide receptor of Aplysia californica involved in the feeding circuit.

Aplysia allatotropin-related peptide and its newly identified d-amino acid-containing epimer both activate a receptor and a neuronal target.

Seasonal adaptations of the hypothalamo-neurohypophyseal system of the dromedary camel.

Enhanced single-cell metabolomics by capillary electrophoresis electrospray ionization-mass spectrometry with field amplified sample injection.

d-Alanine: Distribution, origin, physiological relevance, and implications in disease.

Advancing d-amino acid-containing peptide discovery in the metazoan.

Image-guided MALDI mass spectrometry for high-throughput single-organelle characterization.

Droplet-assisted electrospray phase separation using an integrated silicon microfluidic platform.

Droplet Microfluidics with MALDI-MS Detection: The Effects of Oil Phases in GABA Analysis.

Comparative Analysis of Neuropeptides in Homologous Interneurons and Prohormone Annotation in Nudipleuran Sea Slugs.

Mass Spectrometry Measurements of Neuropeptides: From Identification to Quantitation.

Deterministic Integration of Biological and Soft Materials onto 3D Microscale Cellular Frameworks.

Metabolomics-based mass spectrometry methods to analyze the chemical content of 3D organoid models.

Mass Spectrometry Approaches Empowering Neuropeptide Discovery and Therapeutics.

Profiling of d-alanine production by the microbial isolates of rat gut microbiota.

Profiling 26,000 Aplysia californica neurons by single cell mass spectrometry reveals neuronal populations with distinct neuropeptide profiles.

d-Amino Acids and Classical Neurotransmitters in Healthy and Type 2 Diabetes-Affected Human Pancreatic Islets of Langerhans.

Attomole-Level Multiplexed Detection of Neurochemicals in Picoliter Droplets by On-Chip Nanoelectrospray Ionization Coupled to Mass Spectrometry.

Single cell metabolism: current and future trends.

Chemical Decrosslinking-Based Peptide Characterization of Formaldehyde-Fixed Rat Pancreas Using Fluorescence-Guided Single-Cell Mass Spectrometry.

MALDI-MS screening of microbial colonies with isomer resolution to select fatty acid desaturase variants.

Integrative Multiscale Biochemical Mapping of the Brain via Deep-Learning-Enhanced High-Throughput Mass Spectrometry.

Biodistribution and racemization of gut-absorbed L/D-alanine in germ-free mice.

Relations between Glucose and d-Amino Acids in the Modulation of Biochemical and Functional Properties of Rodent Islets of Langerhans.

Metabolic insights from mass spectrometry imaging of biofilms: A perspective from model microorganisms.

Multiscale biochemical mapping of the brain through deep-learning-enhanced high-throughput mass spectrometry.

Bioinformatics for Prohormone and Neuropeptide Discovery.

Nontargeted Identification of D-Amino Acid-Containing Peptides Through Enzymatic Screening, Chiral Amino Acid Analysis, and LC-MS.

High-resolution H-MRSI at 9.4 T by integrating relaxation enhancement and subspace imaging.

A novel series of metazoan L/D peptide isomerases.

1-Octanol-assisted ultra-small volume droplet microfluidics with nanoelectrospray ionization mass spectrometry.

Novel repurposing of sulfasalazine for the treatment of adrenocortical carcinomas, probably through the SLC7A11/xCT-hsa-miR-92a-3p-OIP5-AS1 network pathway.

Neurochemical and Morphological Comparisons of Motor Nerve Organoids and Spinal-Cord Explants.

Enhancing lipid production in plant cells through automated high-throughput genome engineering and phenotyping.

Isoaspartate-containing galanin in rat hypothalamus.

Factorial-Design-Based Optimization of a Commercial MALDI-2 timsTOF Mass Spectrometer for Lipid Analysis.