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Core - Molecular Biology

    Chapter 10

    Gene Expression

    10.1 : Cell Specific Gene Expression01:58

    10.1 : Cell Specific Gene Expression

    Multicellular organisms contain a variety of structurally and functionally distinct cell types, but the DNA in all the cells originated from the same ...

    13.5K views
    10.2 : Regulation of Expression Occurs at Multiple Steps02:24

    10.2 : Regulation of Expression Occurs at Multiple Steps

    Gene expression can be regulated at almost every step from gene to protein. Transcription is the step that is most commonly regulated. This involves the ...

    22.5K views
    10.3 : Cis-regulatory Sequences02:02

    10.3 : Cis-regulatory Sequences

    Cis-regulatory sequences are short fragments of non-coding DNA that are present on the same chromosomes as the genes that they regulate. These fragments ...

    9.8K views
    10.4 : Cooperative Binding of Transcription Regulators02:13

    10.4 : Cooperative Binding of Transcription Regulators

    Transcriptional regulators bind to specific cis-regulatory sequences in the DNA to regulate gene transcription. These cis-regulatory sequences are ...

    6.4K views
    10.5 : Prokaryotic Transcriptional Activators and Repressors01:58

    10.5 : Prokaryotic Transcriptional Activators and Repressors

    The organization of prokaryotic genes in their genome is notably different from that of eukaryotes. Prokaryotic genes are organized, such that the genes ...

    20.8K views
    10.6 : Operons

    10.6 : Operons

    Prokaryotes can control gene expression through operons—DNA sequences consisting of regulatory elements and clustered, functionally related ...

    15.6K views
    10.7 : The Eukaryotic Promoter Region02:40

    10.7 : The Eukaryotic Promoter Region

    The eukaryotic promoter region is a segment of DNA located upstream of a gene. It contains an RNA polymerase binding site, a transcription start site, and ...

    16.2K views
    10.8 : Co-activators and Co-repressors02:04

    10.8 : Co-activators and Co-repressors

    Gene transcription is regulated by the synergistic action of several proteins that form a complex at a gene regulatory site. This is observed in ...

    7.3K views
    10.9 : Eukaryotic Transcription Activators02:42

    10.9 : Eukaryotic Transcription Activators

    Transcription activators are proteins that promote the transcription of genes from DNA to RNA. In most cases, these proteins contain two separate domains ...

    10.9K views
    10.10 : Eukaryotic Transcription Inhibitors01:52

    10.10 : Eukaryotic Transcription Inhibitors

    Certain biochemical processes, such as embryonic development and cell growth regulation, depend on the repression of specific genes. DNA binding ...

    9.8K views
    10.11 : Combinatorial Gene Control02:33

    10.11 : Combinatorial Gene Control

    Combinatorial gene control is the synergistic action of several transcriptional factors to regulate the expression of a single gene. The absence of one or ...

    8.3K views
    10.12 : Induced Pluripotent Stem Cells

    10.12 : Induced Pluripotent Stem Cells

    Stem cells are undifferentiated cells that divide and produce different types of cells. Ordinarily, cells that have differentiated into a specific cell ...

    3.5K views
    10.13 : Master Transcription Regulators02:23

    10.13 : Master Transcription Regulators

    Master transcription regulators are regulatory proteins that are predominantly responsible for regulating the expression of multiple genes. Often these ...

    6.9K views
    10.14 : Epigenetic Regulation

    10.14 : Epigenetic Regulation

    Epigenetic mechanisms play an essential role in healthy development. Conversely, precisely regulated epigenetic mechanisms are disrupted in diseases like ...

    24.3K views
    10.15 : Genomic Imprinting and Inheritance02:30

    10.15 : Genomic Imprinting and Inheritance

    Diploid organisms inherit genetic material through chromosomes from both parents. Copies of the same gene are known as alleles. In most cases, both ...

    33.3K views
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