Core - Pharmacology

Chapter 1

General Pharmacological Principles

1.1 : Drug Discovery: Overview

1.1 : Drug Discovery: Overview

Drug discovery is a multifaceted process involving extensive screening, testing, and optimization of lead compounds to identify potential new drugs for ...

1.2 : Preclinical Development: Overview

1.2 : Preclinical Development: Overview

Preclinical development consists of a series of tests that ensure the safety and efficacy of a new therapeutic compound before it is tested in humans. ...

1.3 : Clinical Trials: Overview

1.3 : Clinical Trials: Overview

Clinical development focuses on how the drug will interact with the human body and encompasses four key phases of clinical trials, each serving a specific ...

1.4 : Drug Nomenclature

1.4 : Drug Nomenclature

During the development of a new pharmaceutical, the manufacturer initially assigns a code name to the drug. Once approved, the drug receives a United ...

1.5 : Drug Regulation

1.5 : Drug Regulation

Drug regulation encompasses the management of drug usage by evaluating its safety and efficacy through assessments conducted by regulatory authorities. ...

1.6 : Drug Classes and Categories

1.6 : Drug Classes and Categories

Drugs can be classified according to their chemical composition or their intended therapeutic application. For instance, anti-infective agents that ...

1.7 : Drug-Receptor Bonds

1.7 : Drug-Receptor Bonds

Drug-receptor bonds are formed through various chemical forces when drugs interact with target cells. Covalent bonds, strong and irreversible, are ...

1.8 : Drug-Receptor Interactions

1.8 : Drug-Receptor Interactions

Drug-receptor interaction describes the binding of receptors by drugs, but not all drug-receptor interactions result in activation and tissue response. ...

1.9 : Routes of Drug Administration: Overview

1.9 : Routes of Drug Administration: Overview

Drug administration involves delivering drugs to the body through various routes, such as enteral, parenteral, and topical. Enteral administration refers ...

1.10 : Routes of Drug Administration: Enteral

1.10 : Routes of Drug Administration: Enteral

Medications can be administered through the enteral route using liquids, capsules, or tablets. Enteral administration involves drug administration via the ...

1.11 : Routes of Drug Administration: Parenteral

1.11 : Routes of Drug Administration: Parenteral

The administration of drugs via parenteral routes allows for direct drug introduction into the systemic circulation, resulting in high bioavailability ...

1.12 : Additional Routes of Drug Administration

1.12 : Additional Routes of Drug Administration

Choosing the appropriate route of drug administration is significantly influenced by two key factors: the therapeutic objectives and the inherent ...

1.13 : Prescription, Nonprescription and Orphan Drugs

1.13 : Prescription, Nonprescription and Orphan Drugs

Prescription drugs require a prescription from a medical practitioner and can only be obtained from a pharmacy. They have many applications, including ...

1.14 : Factors Affecting Drug Response: Overview

1.14 : Factors Affecting Drug Response: Overview

When it comes to infants and young children, they are typically administered smaller doses of medication in comparison to adults. This is primarily ...

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