Création de sous-50 Nm nanofluidiques Jonctions en PDMS microfluidique Chip via processus d'auto-assemblage des particules colloïdales

We propose a simple self-assembly technique of silica colloidal nanoparticles to create a nanofluidic junction between two microchannels in polydimethylsiloxane (PDMS). Using this technique, a nanoporous bead membrane with a pore size down to ~45 nm was built inside a microchannel and applied to electrokinetic preconcentration of DNA samples.