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Using Optogenetics to Reverse Neuroplasticity and Inhibit Cocaine Seeking in Rats

2.4K Views

09:43 min

October 5th, 2021

DOI :

10.3791/63185-v

October 5th, 2021


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Optogenetics

Chapters in this video

0:04

Introduction

0:46

Rodent Intravenous Catheterization, Virus Delivery, and Optic Fiber Implantation

4:11

Rodent Cocaine Self-Administration and Instrumental Lever Extinction

5:25

In Vivo Optogenetic Induction of Long-Term Depression (LTD)

6:40

Test the Effect of Optogenetic Stimulation on Cue-Induced Cocaine Seeking

7:15

Results: The Behavioral and Histological Analysis after Cocaine Self-Administration Experiments in Rats

9:02

Conclusion

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