JoVE Journal

Behavior

This content is Open Access.

Analysis of Learning and Memory Ability in an Alzheimer's Disease Mouse Model using the Morris Water Maze

18.8K Views

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07:07 min

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October 29th, 2019

DOI :

10.3791/60055-v

October 29th, 2019

•

Huiling Tian¹, Ning Ding², Mengwei Guo¹, Shun Wang¹, Zidong Wang¹, Hao Liu¹, Jiayi Yang¹, Yujie Li³, Jingyu Ren¹, Jing Jiang⁴, Zhigang Li¹

¹School of Acupuncture-Moxibustion and Tuina, Beijing University of Chinese Medicine, ²Guang'anmen Hospital of China Academy of Chinese Medical Science, ³The Third Affiliated Hospital of Beijng University of Chinese Medicine, ⁴School of Nursing, Beijing University of Chinese Medicine

Summary

Herein, a protocol to conduct the Morris water maze tests to evaluate the ability of learning and memory of Alzheimer’s Disease model mice and to assess the effect of manual acupuncture for treating them is described.

Explore More Videos

Morris Water Maze

Alzheimer s Disease

Spatial Learning

Cognitive Function

Task Parameters

Experimental Protocol

Visible Platform Trial

Tracking System

Swimming Trajectories

Cognitive Assessment

Behavioral Experiment

Chapters in this video

0:04

Title

1:22

Experimental Setup

2:25

Morris Water Maze Test

4:40

Results: Effects of Manual Acupuncture on Learning and Memory of Mice with Alzheimer s Disease

5:55

Conclusion

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