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Neuroscience

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Nanyang Technological University

Fluorescence Angiography for Evaluation of Aneurysm Perfusion and Parent Artery Patency in Rat and Rabbit Aneurysm Models

6.9K Views

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04:08 min

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July 24th, 2019

DOI :

10.3791/59782-v

July 24th, 2019

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Fabio Strange¹^,², Sivani Sivanrupan², Basil E. Gruter¹^,², Jeannine Rey², Dominik Taeschler², Javier Fandino¹^,², Serge Marbacher¹^,²

¹Department of Neurosurgery, Kantonsspital Aarau, ²Cerebrovascular Research Group, Department for BioMedical Research (DBMR), University of Bern

Summary

We present a protocol to efficiently evaluate aneurysm perfusion and vessel patency of sidewall aneurysm in rats and rabbits, using fluorescein-based fluorescence video angiography (FVA). With a positive predictive value of 92.6%, it is a simple but very effective and economical method with no special equipment required.

Explore More Videos

Fluorescence Angiography

Aneurysm Perfusion

Parent Artery Patency

Fluorescein Video Angiography

Surgical Technique

Blood Flow Visualization

Disinfection Procedure

Fluorescent Dye Injection

Macroscopic Analysis

Residual Perfusion

Imaging Technique

Chapters in this video

0:04

Title

0:31

Material and Workplace Preparation

1:05

Fluorescein Video Angiography (FVA) and Macroscopic Analysis in a Rabbit

2:31

Results: Patency Testing

3:40

Conclusion

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