Comprehensive Evaluation of the Effectiveness and Safety of Placenta-Targeted Drug Delivery Using Three Complementary Methods

9.6K Views

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09:04 min

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September 10th, 2018

DOI :

10.3791/58219-v

September 10th, 2018

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Baozhen Zhang¹, Zhilong Chen¹^,², Jinyu Han¹^,³, Mengxia Li¹, Nihar R. Nayak⁴, Xiujun Fan¹

¹Laboratory for Reproductive Health, Institute of Biomedicine and Biotechnology, Shenzhen Institutes of Advanced Technology, Chinese Academy of Sciences, ²College of Veterinary Medicine, Hunan Agricultural University, ³Key Laboratory of Chemical Engineering Process and Technology for High-efficiency Conversion, College of Chemistry and Material Sciences, Heilongjiang University, ⁴Department of Obstetrics and Gynecology, Wayne State University School of Medicine

Summary

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Keywords Placenta targeted Drug Delivery

Nanomedicine

In Vivo Fluorescence Imaging

High frequency Ultrasound

Embryonic Development

Fetus

Placenta

Intravenous Nanoparticle Injection

Drug Targeting

Chapters in this video

0:04

Title

1:11

In Vivo Fluorescence Imaging

2:35

High-Frequency Ultrasound (HFUS) Embryonic Development Evaluation

4:28

High Pressure Liquid Chromatography (HPLC) Analysis

6:18

Results: Representative Placenta-Targeted Drug Delivery Analyses

8:12

Conclusion

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