Spinal Cord Lateral Hemisection and Asymmetric Behavioral Assessments in Adult Rats

14.2K Views

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08:46 min

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March 24th, 2020

DOI :

10.3791/57126-v

March 24th, 2020

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Xiao-Jing Lin¹^,²^,³, Shaonan Wen²^,⁶, Ling-Xiao Deng³, Heqiao Dai³, Xiaolong Du³, Chen Chen³^,⁴, Melissa J. Walker³^,⁴, Ting-Bao Zhao¹^,⁵, Xiao-Ming Xu³

¹Department of Spinal Cord Injury and Repair, Trauma and Orthopedics Institute of Chinese PLA, 960th Hospital, Joint Logistics Support Force of PLA, ²Institute of Military Cognition and Brain Sciences, Academy of Military Medical Sciences, Academy of Military Sciences, ³Spinal Cord and Brain Injury Research Group, Stark Neurosciences Research Institute, Department of Neurological Surgery and Goodman Campbell Brain and Spine, Indiana University School of Medicine, ⁴Program in Medical Neuroscience, Paul and Carole Stark Neurosciences Research Institute, Indiana University School of Medicine, ⁵Department of Orthopedics, the Third Affiliated Hospital, Shandong University, ⁶Beijing Computing Center, Beijing Academy of Science and Technology

Summary

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Keywords Spinal Cord Lateral Hemisection

Brown Sequard Syndrome

Asymmetric Behavioral Assessments

Adult Rats

Animal Model

Neurological Impairments

Consistent Natural Hemi section Model

Chapters in this video

0:05

Introduction

1:34

Animal Preparation

2:11

Spinal Hemisection

5:01

Combined Behavior Score for Hemisection (CBS-HX) Assessments

6:37

Results: Representative Neurobehavioral Scoring

8:15

Conclusion

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