JoVE Journal

Medicine

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Nanyang Technological University

Assessment of Cardiac Morphological and Functional Changes in Mouse Model of Transverse Aortic Constriction by Echocardiographic Imaging

The goal of this protocol is to noninvasively assess cardiac structural and functional changes in a mouse model of heart disease created by transverse aortic constriction, using B- and M-mode echocardiography and color/pulse wave Doppler imaging.

Chapters in this video

0:05

Title

0:57

Transverse Aortic Constriction Evaluation by B-Mode and Doppler Imaging

2:47

Parasternal Long Axis View in B- and M-Mode to Assess Cardiac Dimension and Contractility

4:16

Parasternal Short Axis View in B- and M-Mode to Assess Cardiac Morphology and Function

5:05

Apical Four-Chamber View in Doppler Mode to Assess Systolic and Diastolic Function

6:12

Results: Representative Morphological and Functional Post-Surgical Cardiac Assessment

7:44

Conclusion

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