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Investigating the Function of Coronin A in the Early Starvation Response of Dictyostelium discoideum by Aggregation Assays

The social amoeba Dictyostelium discoideum undergoes a developmental transition into a multicellular organism when starved. The evolutionary conserved protein coronin A plays a crucial role in the initiation of development. Using aggregation assays as our main method, we aim to elucidate the role of coronin A in early development.

Chapters in this video

0:05

Title

0:58

Observe the Early Starvation Response of Dictyostelium discoideum by Time-lapse Microscopy

2:14

cAMP Pulsing of Dictyostelium discoideum Cells During Starvation

3:54

Induction of Dictyostelium discoideum Development Through Exposure to Conditioned Medium

5:32

Results: cAMP Pulses Rescue the Early Developmental Defect of corA- Dictyostelium discoideum

6:45

Conclusion

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