The Use of Reverse Phase Protein Arrays (RPPA) to Explore Protein Expression Variation within Individual Renal Cell Cancers
33.5K Views
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12:22 min
•
January 22nd, 2013
DOI :
January 22nd, 2013
•Fiach C. O'Mahony1, Jyoti Nanda1, Alexander Laird1, Peter Mullen2, Helen Caldwell3, Ian M. Overton4, Lel Eory4, Marie O'Donnell1,5, Dana Faratian6, Thomas Powles7, David J. Harrison1,2, Grant D. Stewart1
1Edinburgh Urological Cancer Group, University of Edinburgh, 2School of Medicine, University of St Andrews, 3Division of Pathology, University of Edinburgh, 4MRC Human Genetics Unit, MRC IGMM, University of Edinburgh, 5Department of Pathology, Western General Hospital, 6Breakthrough Breast Cancer Research Unit, University of Edinburgh, 7St Bartholomew's Cancer Institute, Experimental Cancer Medicine Centre, Queen Mary University of London
Chapters in this video
0:05
Title
1:39
Identification of Morphological and Molecular Tumor Heterogeneity
2:58
Protein Extraction from Tumor Samples
4:24
RPPA Printing
6:00
RPPA Protein Detection
9:27
Results: Pre- and Post-TKI-treated Renal Cell Cancer Show Differential Protein Expression
12:06
Conclusion
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