A abordagem do rato Round-janela para ototóxicos Delivery Agent: A rápida e técnica confiável para induzir a degeneração das células da cóclea

Various methods exist for introducing ototoxic agents to the cochleae of animal models. Presented is a surgical protocol for delivery of ototoxic agents to the round window niche. The procedure is reliable, creates targeted intra-cochlear lesions, and avoids mechanical damage to the microarchitecture. Examination of cochlear self-repair/regeneration is possible.