Real-Time Intravital Multiphoton Microscopy to Visualize Focused Ultrasound and Microbubble Treatments to Increase Blood-Brain Barrier Permeability
Please note that all translations are automatically generated. Click here for the English version.
4.2K Views
•
06:29 min
•
February 5th, 2022
DOI :
February 5th, 2022
•Charissa Poon1,2, Melina Mühlenpfordt*3, Marieke Olsman*3, Spiros Kotopoulis4,5, Catharina de Lange Davies3, Kullervo Hynynen1,2,6
1Physical Sciences Platform, Sunnybrook Research Institute, 2Institute of Biomedical Engineering, University of Toronto, 3Department of Physics, Norwegian University of Science and Technology, 4Department of Clinical Medicine, University of Bergen, 5Exact Therapeutics AS, 6Department of Medical Biophysics, University of Toronto
Przeglądaj więcej filmów
Rozdziały w tym wideo
0:07
Introduction
1:18
Material Preparation
1:46
Animal Preparation
3:26
Placement of the Ring Transducer
4:05
Multiphoton Microscopy Imaging
4:30
Ultrasound Exposure
4:56
Representative Results
5:52
Conclusion
Powiązane Filmy
14:10
Contrast Ultrasound Targeted Treatment of Gliomas in Mice via Drug-Bearing Nanoparticle Delivery and Microvascular Ablation
15.9K Views
08:37
Intravital Microscopy of the Mouse Brain Microcirculation using a Closed Cranial Window
17.4K Views
07:42
MRI-guided Disruption of the Blood-brain Barrier using Transcranial Focused Ultrasound in a Rat Model
17.8K Views
09:17
Longitudinal Intravital Imaging of Brain Tumor Cell Behavior in Response to an Invasive Surgical Biopsy
7.3K Views
08:39
Multiplexing Focused Ultrasound Stimulation with Fluorescence Microscopy
8.1K Views
08:24
Extended Time-lapse Intravital Imaging of Real-time Multicellular Dynamics in the Tumor Microenvironment
8.0K Views
06:02
Multi-timescale Microscopy Methods for the Characterization of Fluorescently-labeled Microbubbles for Ultrasound-Triggered Drug Release
3.8K Views
08:02
A High-Throughput Image-Guided Stereotactic Neuronavigation and Focused Ultrasound System for Blood-Brain Barrier Opening in Rodents
4.7K Views
07:50
Multiphoton Intravital Imaging for Monitoring Leukocyte Recruitment during Arteriogenesis in a Murine Hindlimb Model
1.3K Views
03:32
Monitoring Blood-Brain Barrier Opening in Rats with a Preclinical Focused Ultrasound System
483 Views
Copyright © 2025 MyJoVE Corporation. Wszelkie prawa zastrzeżone