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Medicine

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Nanyang Technological University

An Image Guided Transapical Mitral Valve Leaflet Puncture Model of Controlled Volume Overload from Mitral Regurgitation in the Rat

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6.9K Views

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07:42 min

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May 19th, 2020

DOI :

10.3791/61029-v

May 19th, 2020

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Daniella Corporan¹, Takanori Kono¹, Daisuke Onohara¹, Muralidhar Padala¹^,²

¹Structural Heart Research and Innovation Laboratory, Carlyle Fraser Heart Center, Emory University Hospital Midtown, ²Division of Cardiothoracic Surgery, Joseph P. Whitehead Department of Surgery, Emory University School of Medicine

Podsumowanie

A rodent model of left heart volume overload from mitral regurgitation is reported. Mitral regurgitation of controlled severity is induced by advancing a needle of defined dimensions into the anterior leaflet of the mitral valve, in a beating heart, with ultrasound guidance.

Przeglądaj więcej filmów

Mitral Regurgitation

Transapical Puncture

Controlled Volume Overload

Echocardiographic Imaging

Needle Placement

Real time Ultrasound Guidance

Anterior Mitral Leaflet

Color Doppler Imaging

Pursestring Suture

Chest Tube Insertion

Cardiac Function

Rozdziały w tym wideo

0:05

Introduction

0:54

Echocardiography-Guided Mitral Regurgitation (MR)

2:40

Animal Recovery and Post-Operative Care

4:45

MR Severity Validation

6:01

Results: Representative Cardiac Chamber Remodeling and MR Severity

7:03

Conclusion

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