Development of a Backbone Cyclic Peptide Library as Potential Antiparasitic Therapeutics Using Microwave Irradiation

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11.7K Views

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08:48 min

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January 26th, 2016

DOI :

10.3791/53589-v

January 26th, 2016

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Nir Qvit¹, Opher S. Kornfeld¹

¹Department of Chemical and Systems Biology, Stanford University School of Medicine

Podsumowanie

Rozdziały w tym wideo

0:05

Title

0:27

Fmoc-protected Amino Acid Coupling

2:03

Anhydride/Acid Coupling

3:01

N-methyltrityl (Mtt) Protecting Group Deprotection

4:18

Cyclization of the Linear Peptide

4:57

Cleavage and Deprotection of Side-chain Groups

6:04

Kaiser (Ninhydrin) Test

7:01

Results: Synthesis of Cyclic Peptides Using Microwave Irradiation

7:45

Conclusion

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