JoVE Journal

Medicine

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Nanyang Technological University

תאי גזע מהונדסים חסינות בהתבסס נגד HIV זיהום במודל העכבר האנושי

This protocol describes the methods in constructing a humanized bone-marrow/liver/thymus mouse model with stem cell-based engineered immunity against HIV infection.

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Chapters in this video

0:05

Title

2:18

Liver Processing

5:18

Tissue Transplantation to Construct Genetically Engineered Mice

9:28

Results: Characteristics of CD4 Chimeric Antigen Receptor Modified Cells

10:39

Conclusion

1:07

Construction of Humanized Mice Engineered with CD4 Chimeric Antigen Receptor: Thymus Processing

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